Rate ratios for endometrial cancer, 95% confidence intervals, number of cases, and total person years by age of diagnosis and disease laterality of relative with breast cancer
| 1st degree relative | ||||||
|---|---|---|---|---|---|---|
| Age at diagnosis* | Laterality status | |||||
| Reference group | <50 | ≥50 | Unknown | Unilateral | Bilateral | Unknown |
| *Age at diagnosis is the age of youngest relative in that category with breast cancer. | ||||||
| All analyses are adjusted for attained age, race, menopausal status, BMI, number of relatives in each category (except mother’s category), and personal breast cancer diagnosis (except the category of women with a personal history of breast cancer). | ||||||
| Women who did not have relatives with breast cancer in that category formed the reference group for each group. | ||||||
| 1.0 | 0.8 (0.5 to 1.2) | 1.0 (0.8 to 1.3) | 0.9 (0.6 to 1.3) | 0.8 (0.6 to 1.1) | 1.4 (0.8 to 2.4) | 1.0 (0.8 to 1.3) |
| CA/PY | 24/23 292 | 69/46 193 | 25/22 280 | 49/42 948 | 15/8349 | 55/41 562 |
| Women with a personal history of breast cancer | ||||||
| 1.0 | 0.5 (0.2 to 1.7) | 0.8 (0.4 to 1.5) | 1.2 (0.5 to 2.8) | 0.6 (0.2 to 1.3) | 1.8 (0.6 to 5.2) | 0.8 (0.4 to 1.7) |
| CA/PY | 3/3187 | 10/6862 | 6/3053 | 6/5924 | 4/1351 | 9/5932 |
| Mother with breast cancer | ||||||
| Mother’s age at diagnosis* | Mother’s laterality status | |||||
| Reference group | <50 | ≥50 | Unknown | Unilateral | Bilateral | Unknown |
| 1.0 | 0.9 (0.4 to 1.7) | 1.0 (0.8 to 1.4) | 0.8 (0.5 to 1.4) | 0.9 (0.6 to 1.3) | 1.5 (0.7 to 3.1) | 1.0 (0.7 to 1.5) |
| CA/PY | 8/7622 | 42/29 301 | 14/13 814 | 28/24 290 | 7/4274 | 29/22 509 |
| Sister with breast cancer | ||||||
| Sister’s age at diagnosis* | Sister’s laterality status | |||||
| Reference group | <50 | ≥50 | Unknown | Unilateral | Bilateral | Unknown |
| 1.0 | 0.8 (0.5 to 1.4) | 1.0 (0.7 to 1.4) | 1.1 (0.6 to 1.8) | 0.8 (0.5 to 1.2) | 1.4 (0.7 to 2.7) | 0.9 (0.6 to 1.4) |
| CA/PY | 14/13 707 | 30/20 349 | 15/11 015 | 24/20 630 | 9/4558 | 26/20 224 |
| Daughter with breast cancer | ||||||
| Daughter’s age at diagnosis* | Daughter’s laterality status | |||||
| Reference group | <50 | ≥50 | Unknown | Unilateral | Bilateral | Unknown |
| 1.0 | 0.7 (0.2 to 2.2) | – | 1.3 (0.3 to 5.4) | 0.5 (0.1 to 2.1) | 1.1 (0.1 to 9.0) | 1.2 (0.3 to 5.1) |
| CA/PY | 3/2474 | 0 | 2/890 | 2/2294 | 1/313 | 2/1134 |