Table 1

Clinical characteristics of the VWS patients in the study

Family No		Subject No		(ID)		Genotyped		Sex		VWS phenotype^1-150
Family No		Subject No		(ID)		Genotyped		Sex		CL/P	CP	Lip pits
57	II.1	(6387)	Yes	M		+
	II.2	(6388)	Yes	F	+
	II.3	(6389)	Yes	M		+
	II.5	(6381)	Yes	M		+
	III.3	(6397)	Yes	F		sm
	III.5	(6396)	Yes	M			+
	III.7	(6383)	Yes	M		+
	III.9	(6385)	Yes	F		+
	III.10	(6386)	Yes	M		sm	wl
	IV.2	(6394)	Yes	F		+
	IV.4	(6399)	Yes	F		+	wl
59	II.5	(5)		M		+
	III.1	(16)		M		+
	III.3	(6405)	Yes	F		+	+
	IV.1	(6402)	Yes	M		+
	IV.5	(6410)	Yes	M		+	+
60	IV.2	(6414)	Yes	F		+
	IV.6	(6428)	Yes	F		+
	IV.7	(6426)	Yes	M		sm	+
	IV.10	(34)		M		+
	V.1	(6411)	Yes	M		sm
	V.2	(6412)	Yes	F	+
61	II.1	(5)		M		+
	III.2	(6379)	Yes	F		+
	III.3	(7)		M		+
	IV.1	(6376)	Yes	M		+
	IV.2	(6377)	Yes	F		+	+
62	II.1	(6432)	Yes	M	+		+
	III.1	(6435)	Yes	F		+
	III.2	(6433)	Yes	M		sm	+

↵1-150 + = present; blank = not observed; CL/P = cleft lip with and without cleft palate; CP = cleft palate; sm = submucous cleft palate; wl = “wave-like” lower lip.