Relative risk of thyroid cancer for relatives of thyroid cancer patients
| Relatedness | Gender | No | Ratio | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Obs | Exp | O/E | 95% CI | ||||||
| (A) All probands (n=712) | |||||||||
| 1st degree | Male | 28 | 6.83 | 4.10 | 2.74–5.90 | ||||
| 1st degree | Female | 32 | 16.56 | 1.93 | 1.31–2.70 | ||||
| 2nd degree | Male | 23 | 12.17 | 1.89 | 1.12–2.66 | ||||
| 2nd degree | Female | 52 | 32.90 | 1.58 | 1.15–2.01 | ||||
| 3rd degree | Male | 35 | 22.55 | 1.55 | 1.04–2.06 | ||||
| 3rd degree | Female | 81 | 55.96 | 1.45 | 1.14–1.77 | ||||
| Pooled | Male | 3.83 | 1.63–5.04 | ||||||
| Pooled | Female | 2.08 | 1.58–2.58 | ||||||
| (B) Male probands (206) | |||||||||
| 1st degree | Male | 13 | 1.95 | 6.67 | 3.57–11.29 | ||||
| 1st degree | Female | 14 | 4.92 | 2.84 | 1.55–4.74 | ||||
| 2nd degree | Male | 8 | 3.63 | 2.20 | 0.94–4.35 | ||||
| 2nd degree | Female | 14 | 9.77 | 1.43 | 0.78–2.39 | ||||
| 3rd degree | Male | 15 | 7.56 | 1.98 | 0.98–2.98 | ||||
| 3rd degree | Female | 18 | 17.34 | 1.04 | 0.56–1.52 | ||||
| Pooled | Male | 6.52 | 3.56–9.48 | ||||||
| Pooled | Female | 2.55 | 1.41–3.70 | ||||||
| (C) Female probands (506) | |||||||||
| 1st degree | Male | 15 | 4.88 | 3.07 | 1.71–5.03 | ||||
| 1st degree | Female | 18 | 11.64 | 1.55 | 0.92–2.43 | ||||
| 2nd degree | Male | 15 | 8.54 | 1.76 | 0.87–2.65 | ||||
| 2nd degree | Female | 38 | 23.13 | 1.64 | 1.12–2.16 | ||||
| 3rd degree | Male | 20 | 14.99 | 1.33 | 0.75–1.92 | ||||
| 3rd degree | Female | 63 | 38.62 | 1.63 | 1.23–2.03 | ||||
| Pooled | Male | 2.92 | 1.70–4.14 | ||||||
| Pooled | Female | 2.02 | 1.47–2.57 | ||||||