Surgery | Screening | ||||||
---|---|---|---|---|---|---|---|
(n=23) | Range | % | (n=26) | Range | % | ||
Demographic characteristics | |||||||
Mean age | 44.4 | 32–62 | — | 36.5 | 28–50 | — | |
Mean age at surgery | 38.8 | 31–45 | — | — | — | — | |
Mean time since surgery (y) | 5.5 | 0.5–25 | — | — | — | — | |
Single | 0 | — | — | 4 | — | 15 | |
Married/living as married | 21 | — | 91 | 14 | — | 54 | |
Divorced/separated | 2 | — | 9 | 8 | — | 31 | |
Women with children | 23 | — | 100 | 19 | — | 73 | |
Pregnant | 0 | — | — | 1 | — | 4 | |
Family history of ovarian and breast cancer | |||||||
Maternal family history | 20 | — | 87 | 20 | — | 77 | |
Paternal family history | 1 | — | 4 | 5 | — | 19 | |
Maternal + paternal family history | 2 | — | 9 | 1 | — | 4 | |
Total number of affected relatives | 98 | 2–8 | — | 97 | 1–91-150 | — | |
Mean number of affected relatives | 4.3 | — | — | 4.0 | — | — | |
Women with affected 1st degree relatives | 21 | — | 91 | 18 | — | 69 | |
Women with affected 2nd degree relatives | 19 | — | 83 | 23 | — | 88 | |
Personal history of breast cancer | — | — | — | 4 | — | 15 | |
Cancer risk management history | |||||||
Cancer genetic counselling pre-surgery | 6 | — | 26 | 19 | — | 73 | |
Cancer genetic counselling post-surgery | 5 | — | 22 | — | — | — | |
Ovarian screening pre-surgery | 16 | — | 70 | 261-151 | — | 96 | |
Ovarian screening post-surgery | 3 | — | 13 | — | — | — | |
Surgical procedures 1-152 | |||||||
BSO + hysterectomy | 16 | — | 70 | — | — | — | |
BSO only | 71-153 | — | 30 | — | — | — | |
BRCA1/2 mutation status | |||||||
Mutation search initiated in family | 3 | — | 13 | 12 | — | 44 | |
Mutation positive | 1 | — | 4 | 1 | — | 4 | |
Mutation negative | 1 | — | 4 | — | — | — |
↵1-150 Women with only one affected relative were themselves affected with breast cancer.
↵1-151 One woman had ceased screening and another was about to start screening.
↵1-152 In five cases, oophorectomy was performed following abnormal screening results/during an exploratory operation.
↵1-153 Four women had previously undergone therapeutic hysterectomy.