Table 1

Results of two point linkage analysis for chromosome 6 markers

Marker1-150Map distance (cM)Lod score at θ =
0.00.010.050.10.20.30.41-151
Chr 6p21
 d6s10544.41−∞−0.440.150.310.320.220.10
−∞−0.140.430.580.540.370.17
d6s101445.501.531.501.371.210.880.570.27
1.081.060.980.880.660.420.19
d6s29149.501.631.591.441.250.870.500.20
1.311.281.181.030.730.430.19
d6s242753.812.112.071.901.701.260.810.38
2.232.192.041.841.400.920.43
d6s42660.442.332.292.111.891.410.930.45
2.672.622.442.201.681.110.53
d6s1017 63.28 1.29 1.26 1.12 0.95 0.62 0.33 0.12
1.25 1.22 1.10 0.95 0.64 0.37 0.15
d6s27166.371.401.371.271.140.880.610.32
0.950.940.880.810.660.480.26
d6s1280 73.13 1.29 1.26 1.15 1.02 0.76 0.51 0.26
0.82 0.80 0.75 0.68 0.53 0.37 0.20
d6s1960 76.62 −∞ −2.77 −1.42 −0.89 −0.44 −0.22 −0.10
−∞ −2.73 −1.37 −0.82 −0.36 −0.17 −0.08
Chr 6q25
 d6s363161.59−∞−0.75−0.120.100.230.220.14
−∞−0.74−0.100.130.270.250.16
d6s1305164.781.791.751.631.461.130.780.41
1.131.111.060.980.800.580.32
d6s305 166.39 2.27 2.23 2.06 1.84 1.38 0.91 0.44
1.81 1.78 1.68 1.53 1.19 0.81 0.41
d6s980167.781.581.551.451.321.040.740.40
1.051.041.000.940.790.580.33
d6s1599169.950.760.750.690.610.470.320.17
0.790.770.720.660.520.360.19
d6s1277 173.31 −∞ −0.19 0.41 0.59 0.62 0.51 0.30
−∞ −0.09 0.51 0.68 0.69 0.55 0.32
  • 1-150 In italics are markers that were added after the initial screening. Additional markers typed in the same regions were not informative in our pedigree.

  • 1-151 Results obtained in the affecteds only and reduced penetrance analyses are reported in the first and second lines respectively for each marker.