Allele and genotype frequencies at the ACE locus in necropsy confirmed AD cases and non-demented elderly controls
| Controls | % | Cases | % | Odds ratios with 95% CI | |
| Allele D | 361 | 53 | 247 | 52 | 1 |
| Allele I | 323 | 47 | 231 | 48 | 1.05 (0.83–1.32) |
| Total | 684 | 100 | 478 | 100 | |
| Genotype DD | 79 | 23 | 68 | 28 | 1 |
| Genotype DI | 203 | 59 | 111 | 46 | 0.64 (0.43–0.95) |
| Genotype II | 60 | 18 | 60 | 25 | 1.16 (0.72–1.89) |
| Total | 342 | 100 | 239 | 100 |
Allele I v D: χ2 1=0.14; p=0.71.
Genotypes: χ2 2=9.81; p=0.007.