Table 1

Objective measures of sleep in Smith-Magenis syndrome

Common deletion Uncommon deletion
Number with finding/total tested1-150 Number with finding/total tested1-150
Epworth sleepiness scale (score >10)13/21 (62)4/5 (80)
Total sleep time (<7 hours)8/23 (35)4/5 (80)
Percentage REM sleep13/23 (57)5/5 (100)
 Decreased (<18%)8/23 (35)3/5 (60)
 Increased (>25%)5/23 (22)2/5 (40)
Spontaneous awakenings (⩾10)20/23 (87)5/5 (100)
Multiple sleep latency test (average latency <10 minutes)10/21 (48)3/5 (60)
6-Sulphatoxymelatonin (inversion of normal rhythm)16/16 (100)2/3 (67)
  • 1-150 Percentage given in parentheses.