Subjects | Clinical presentation1-150 1-152 | Age at diagnosis polyps/cancer1-153 | Number of adenomas | Exon 14 mutation |
II.1 | 1-151Symptomatic | ? | ? | NT |
II.3 | 1-151Symptomatic | ? | ? | NT |
III.1 | 1-151Symptomatic | ? | ? | NT |
III.4 | 1-151Symptomatic | ? | ? | NT |
III.5 | Symptomatic | 61/61 | >100 | Present |
IV.1 | Symptomatic | 46 | >100 | Present |
IV.2 | Call up | 44 | 0 | Absent |
IV.3 | Call up | 42 | 0 | Absent |
IV.4 | Symptomatic | 40 | 6 | Present |
IV.5 | Call up | 36 | 0 | Absent |
IV.6 | Call up | 34 | 0 | Absent |
IV.9 | NK | 34 | NK | NT |
IV.10 | Symptomatic | 44 | 7 | Present |
IV.11 | Call up | 36 | 0 | Absent |
IV.12 | Call up | 40 | 0 | Absent |
IV.13 | Call up | 38 | 0 | Present |
IV.14 | Symptomatic | 34/34 | >100 | Present |
IV.15 | Call up | 39 | 1 | Absent |
IV.16 | Symptomatic | 36/36 | >100 | Present |
IV.17 | NK | 32 | NK | NT |
IV.18 | NK | 31 | NK | NT |
IV.19 | NK | 29 | NK | NT |
IV.20 | Call up | 25 | 0 | Absent |
V.1 | Call up | 15 | 0 | Present |
V.2 | Call up | 13 | 0 | Absent |
V.3 | NK | 11 | NK | Absent |
V.4 | NK | 10 | NK | Absent |
V.6 | NK | 11 | NK | Present |
V.7 | NK | 10 | NK | Absent |
V.8 | NK | 2 | NK | NT |
↵1-150 Symptomatic, patients showing symptoms of FAP and/or CRC.
↵1-151 Symptomatic, no data available.
↵1-152 No extracolonic manifestations were present in affected subjects.
↵1-153 Unaffected subjects and asymptomatic gene carriers, actual age, and age at DNA test are given.
Call up, called for endoscopic examination as at risk subjects; NK, not known; NT, not tested.