Frequency of disease manifestations in AFD males
| Disease manifestation | Present in % patients | Number of patients investigated |
| Neuropathic pain | 77 | 93 |
| Angiokeratoma | 71 | 73 |
| Hypohidrosis | 56 | 52 |
| TIA or CVA (excluded are children <18 years) | 24 | 70 |
| End stage renal failure (excluded are children <18 years) | 30.8 | 84 |
| Proteinuria | 84 | 44 |
| Abnormal renal function | 47 | 60 |
| Ankle swelling | 45 | 76 |
| Chest pain/palpitation | 56 | 61 |
| Left ventricular hypertrophy | 88 | 34 |
| Heart valve abnormalities | 29 | 34 |
| Lymphoedema | 14 | 72 |
| GI symptoms | 69 | 70 |
| Fatigue | 62 | 61 |
| Dysmorphic face | 56 | 41 |
| Self reported hearing loss | 41 | 61 |
| Abnormal audiogram | 78 | 23 |
| Tinitus | 38 | 60 |
The percentage of patients with cerebrovascular involvement is lower than in table 2, as several patients had both TIA and CVA. The numbers of patients represent those who were investigated.