Table 6

Clinical data II

p=Class IClass IIClass IIIClass IVClass V
UFAllUF(n)UF(n)All(n)UF(n)All(n)UF(n)All(n)UF(n)
Walk by 5 y6-150 2.9×10−3 1.1×10−5 50(20)100(7)96(25)86(7)94(18)93(15)97(35)100(7)
Feeding problems (NS)0.6×10−1 1.2×10−1 70(20)80(5)75(12)100(5)83(18)80(10)46(24)63(8)
Simple commands6-150 3.1×10−3 1.2×10−3 53(17)100(4)91(11)100(7)100(13)100(13)100(13)100(5)
Seizures6-150 6.3×10−4 6.8×10−4 100(21)43(7)45(31)29(7)59(27)53(15)73(48)60(10)
Significant seizures6-150 1.0×10−4 8.3×10−8 90(21)14(7)12(26)14(7)17(18)53(15)41(41)40(10)
Hypopigmented6-150 3.3×10−7 2.8×10−8 90(21)17(6)20(20)0(7)14(22)15(13)23(43)44(9)
  • Percentages of patients with each phenotype are indicated under category, with the sample size shown in parentheses.

  • UF = University of Florida set only.

  • All = combined data from UF and published reports.

  • 6-150 Significant in both data sets.

  • NS = not significant.