Patient | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
III.5 | III.7 | III.8 | III.10 | III.11 | IV.1 | IV.2 | IV.3 | IV.4 | IV.5 | IV.6 | IV.7 | IV.9 | IV.10 | IV.12 | |
Age at onset of symptoms (y) | 30 | 20 | 20 | 15 | 21 | 15 | 14 | 3 | 10 | 10 | 8 | 5 | 18 | 13 | 2 |
Age at examination (y) | 54 | 64 | 51 | 42 | 47 | 25 | 16 | 36 | 34 | 29 | 23 | 8 | 20 | 16 | 26 |
Pain in limbs | PMo | PMi | PMi | PMi | PMi | PMi | PMi | PMo | PMo | PMo | PMo | PMi | A | A | PS |
Easy fatiguability | PMo | PMi | A | PMi | A | PMi | A | PMo | PMi | PMo | PMo | A | A | PMi | PMo |
Headache | A | A | A | PMi | A | A | PMi | A | PMi | A | A | A | PMi | A | A |
Poor appetite | A | A | A | PMi | A | PMi | A | A | A | A | A | A | A | A | PMi |
Poor muscle mass | A | A | A | A | A | A | A | PMi | A | PMo | A | PMi | A | A | PMo |
Waddling gait | PMi | PMi | A | A | A | PMi | A | PMi | PMi | PMo | PMo | A | A | A | PS |
Radiographic bone changes | PMo | PS | PMo | PMo | PMi | PMo | PMi | PS | PS | PS | PS | PMi | PMi | PMi | PS |
Haemoglobin (g/dl) | 13.6 | 13.2 | 14.9 | 12.9 | 12.9 | 15.3 | 13.3 | 13.7 | 14.5 | 14.6 | 13.3 | 12.8 | 13.9 | 14.7 | 13.7 |
Erythrocyte sedimentation rate mm/h | 14 | 28 | 1 | 3 | 11 | 9 | 11 | 13 | 16 | 15 | 6 | 11 | 10 | 4 | 16 |
Alkaline phosphatase (U/l) | 27 | 42 | 81 | 24 | 33 | 28 | 20 | 35 | 52 | 57 | 203 | 105 | 46 | 71 | 97 |
P, present; A, absent; S, severe; Mo, moderate; Mi, mild.