Table 1

Clinical characteristics and amplification data of primary tumour samples and cell lines

Sample NoCodeDxGenderAge (y)OutcomeCGHEnhanced RLGS fragments
4C20 (2)4C23 (2)4F62 (2)3D45 (ND)3C2 (ND)3F6 (ND)3G68 (ND)3C15 (ND)3C36 (ND)5C10 (ND)5B35 (ND)4C3 (8)3B35 (8)4A5 (2)4A23 (2)3C25 (2)4F53 (2)3G75 (ND)5E60 (ND)
10107MBM26D
21014MBF2A+
39704P191MBM7A
49707P304MBM3D
59609P256MBM6D+2p24, +3p25, +7q32-+++
35, −9q, +10p, −10q23-ter, +12p13, +13q32, −15q26, +18, +19p13.3, −19q13.3-ter, −20p13, +21, −Xq26-ter
69601P300MBM4A-4q26-ter, +7q11.21,−8p23, +8q23-ter, −9p, −16q++++
79501P002MBM7A++
89503P010MBM9A+4q16, +5p15, −9q++++
99712P611MBF12A
109410P009MBM16A+
119001Z04MBM6A
129812P5013MBM14A+
139501P050MBM6A
149611P246MBF5A
159709P601MBM6A
169708P618MBF14A
179903P901MBM6A+++
189001EE01MBM6A
199905P6002MBM6A
20203MBF4A+
219805P620PN1-150 F7D+++++++++
229501P003PNM3D
239602P366PNM4A
249408P004PNF3D
258910Z01PNM6?+
26D341-MED++
27D283-MED+
28Daoy
29MMH-MED-1
30MMH-PNET-5
  • Dx, diagnosis; MB, medulloblastoma; PN, supratentorial PNET, A, alive; D, dead; ?, lost to follow up; + enhanced RLGS fragment.

  • 1-150 Secondary tumour 2 years after chemotherapy and radiation for a primary medulloblastoma.

  • The chromosomal location ((2), (8), or (ND), chromosome 2, 8, or assignment not possible) of RLGS fragments was determined using the CA-RLGS profile.22