Comparison of haplotype frequencies between HSCR patients, non-transmitted chromosomes of their parents, and control population. (Both homozygous and heterozygous parents are included)
| Haplotypes | HSCR patients* (n=62 patients and 124 chromosomes) | Non-transmitted chromosomes (107 chromosomes) | Control population (n=65 unrelated subjects and 130 chromosomes) |
| A | 10 | 27 | 47 |
| B | 38 | 12 | 8 |
| C | 25 | 5 | 4 |
| D | 15 | 26 | 26 |
| E | 3 | 5 | 8 |
| F | 7 | 1 | 0 |
| G | 9 | 17 | 23 |
| H | 9 | 2 | 6 |
| I | 4 | 2 | 7 |
| J | 1 | 2 | 0 |
| K | 2 | 0 | 0 |
| L | 1 | 8 | 1 |
| Total | 124 | 107 | 130 |
Comparison of transmitted vnon-transmitted: χ2 11 = 53.1, p<0.0001.
Comparison of non-transmitted v control: χ2 10 = 19.1, p=0.039.