Table 1

Clinical features present in 205 patients with Currarino syndrome

Feature Percentage
Bowel obstruction in infancy16
Chronic constipation in childhood41
Perianal sepsis11
Renal/urinary tract problems35
Gynaecological malformation19 females
Meningitis11
Spinal cord tethering14
Anterior meningocele50
Presacral mass other (eg teratoma/
lipoma/cyst)		42
Asymptomatic331-150

  • ↵1-150 Asymptomatic subjects often have visible sacral defects onx ray; 13/90 (14.4%) of the asymptomatic cohort in our own series had a visible sacral defect. In only two cases was a mutation detected in an asymptomatic subject with no signs onx ray.