(1) | Three first or second degree relatives with breast or ovarian cancer |
(2) | Two first or second degree relatives with breast cancer diagnosed under 60 years of age or ovarian cancer at any age |
(3) | One first degree relative with (i) breast cancer diagnosed under 40 years of age, or (ii) bilateral breast cancer, or (iii) male breast cancer |
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For colorectal cancer, one of the following: |
(1) | A first degree relative plus two other relatives with colorectal cancer and (i) one case diagnosed under 50 years of age, and (ii) one case a first degree relative of the other two, and (iii) at least two generations affected |
(2) | A first degree relative with colorectal cancer diagnosed under 45 years of age |