Table 1

Results of LOH studies at NF1 and flanking polymorphisms in four patients, screened with eight intragenic and five extragenic markers. Black circles denote undeleted regions, white circles denote LOH, black squares denote uninformative loci, and ND denotes samples that would not PCR for that particular marker

Tumour		Marker		Marker reference
Tumour		T11	T14	Marker reference		T15	T19	T25	T33.1	T33.2	T68.1	T68.2	T68.3
UT172	•	•	•	•	•	•	•	○	○	○	16
HHH202	•	•	•	•	•	•	•	ND	ND	ND	17
NF1- E5 RFLP (exon 5)	•	○	○	○	○	•	•	•	•	•	18
NF1- exon 13	•	•	•	•	•	•	•	○	○	○	19
NF1- EV120 (intron 27b)	○	•	○	•	•	○	○	○	○	○	20
NF1- 24.8 (intron 27b)	○	•	○	•	•	○	○	•	•	•	21
NF1- 28.4 (intron 27b)	○	•	○	•	•	•	•	•	•	•	21
NF1- 53.0 (intron 38)	○	•	○	•	•	○	○	○	○	○	22
NF1- RsaI RFLP (intron 39)	○	•	•	•	•	•	•	○	○	○	23
NF1- PacI RFLP (intron 41)	○	•	•	•	•	•	•	•	•	•	24
3′ C3	•	•	○	•	•	•	•	•	•	•	25
EW207-17cen-q12	•	•	•	•	•	•	•	•	•	•	26
D17S250 (mfd 15)	○	•	○	•	•	•	•	•	•	•	27