Microsatellite instability (MSI) status and hMSH2 and hMLH1 germline mutations in early onset colorectal cancer patients with a family history
| Patient | Age | Colon cancer site |
Synchronous metachronous cancer | MSI | PTT | SSCP |
MMR gene alteration/ effect on coding sequence |
| SI509 | 48 | L | Gastric | − | − | − | − |
| TO502 | 34 | Sigmoid | − | − | − | − | − |
| SI533 | 41 | Caecum | Ileum | + | − | − | − |
| SI526 | 46 | Rectum | − | − | − | − | − |
| SI502 | 23 | Rectum | − | − | − | − | − |
| SI625 | 48 | R | + | NT | − | − | − |
| SI511 | 30 | Sigmoid | − | NT | − | − | − |
| TO622 | 47 | R | − | − | − | − | − |
| CA68 | 30 | Sigmoid | − | + | − | − | − |
| SI531 | 44 | Sigmoid | − | + | − | − | − |
| SI515 | 49 | R | + | − | − | − | − |
| TO514 | 46 | R | − | − | − | − | − |
| SI507 | 32 | R | − | NT | − | − | − |
| TO605 | 38 | R | − | + | − | − | − |
R, right; L, left; NT, not tested.