Summary of PTEN variants in women with multiple primary tumours
| Sample | Mutation | Amino acid change | Cancer diagnosis | Family history2-150 | ||||
| 1 | 158 GTA→CTA | 158 Val→Leu | Invasive ductal breast cancer | None | ||||
| Lower genital tract cancer | ||||||||
| 2 | 158 GTA→CTA | 158 Val→Leu | Lymphoma | Colon cancer | ||||
| 130 CGA→CGC | 130 Arg→Arg | Invasive breast cancer | ||||||
| Invasive breast cancer | ||||||||
| 3 | 119 GTT→CTT | 119 Val→Leu | Endometrial cancer | None | ||||
| Bilateral ovarian cancer | ||||||||
| 4 | 119 GTT→CTT | 119 Val→Leu | Lung adenocarcinoma | None | ||||
| Invasive ductal breast cancer | ||||||||
| 5 | 119 GTT→CTT | 119 Val→Leu | Invasive ductal breast cancer | Prostate | ||||
| Endometrial cancer | ||||||||
↵2-150 Family history cancer of female breast, colon, prostate, endometrial, ovarian, or melanoma.