Table 1

Distribution of cystic fibrosis patients diagnosed before the age of 5 by age groups in Saguenay-Lac-Saint-Jean, (A) by genotype, (B) by mutation

0–10 years10.1–20 yearsOver 20 yearsAll ages
No%No%No%No%
(A) Genotype
ΔF508/ΔF50815 (1)40.521 (2)36.218 (3)42.954 (6)39.4
ΔF508/621+1G→T12 (1)32.416 (1)27.610 (11-150)23.838 (31-150)27.7
ΔF508/A455E12.7610.3511.9128.8
ΔF508/I148T12.711.721.5
ΔF508/Y1092X3 (1)5.212.44 (1)2.9
ΔF508/Q890X12.410.7
ΔF508/R1158X12.410.7
621+1G→T/621+1G→T2 (1)5.446.912.47 (1)5.1
621+1G→T/A455E12.746.937.185.8
621+1G→T/711+1G→T2 (1)5.42 (1)3.44 (2)2.9
621+1G→T/Y1092X12.710.7
621+1G→T/S489X12.710.7
621+1G→T/G85E1 (1)1.71 (1)2.42 (2)1.5
A455E/R117C12.710.7
N1303K/I148T12.410.7
Total375842137
Death(4)10.8(6)10.3(51-150)11.9(151-150)10.9
(B) Mutation
ΔF50816 (1)43.225 (3)43.121 (3)51.262 (7)45.6
621+1G→T18 (3)48.623 (3)39.712 (21-150)29.353 (81-150)39.0
A455E38.11017.2819.52115.4
Total375841136
Death(4)10.8(6)10.3(51-150)(12.2)(151-150)(11.0)
  • ( ): Number of deaths.

  • 1-150 Including one accidental death.