Sex | M | | M | | M | | F | | M |
Gestation | 36 | | 37 | | 42 | | 95 | | 36 |
Growth | | | | | | | | | |
Height (centile) | 50–75 | | 75–90 | | 75 | | | | 10–25 |
Lean build | | | + | | + | | | | |
Long limbs | | | + | | | | | | |
BW (g) | 2955 | | 2450 | | 3717 | | 3150 | | 2600 |
(Centile) | 50–90 | | 10 | | 10–50 | | 10–50 | | 10–50 |
FTT | | | + | | | | | | + |
CNS/development | | | | | | | | | |
Developmental delay/IQ | +/46–50 | | +/67–77 | | Language/ND | | | | +/ND |
Hypotonia | | | | | | | | | + |
Craniofacial | | | | | | | | | |
HC (centile) | 2–50 | | 25 | | 2–50 | | 50–98 | | <2 |
Plagiocephaly | | | | | | | + | | + |
Double scalp whorl | | | | | | | + | | + |
Protruding ears | | | | | + | | + | | + |
Ear creases | | | | | + | | | | |
Long face | | | | | + | | | | |
Long nose | | | | | + | | | | |
Palpebral fissures | | | | | | | | | |
Long | | | + | | + | | | | |
Upward slanting | | | + | | + | | | | |
Hypocanthus | | | | | + | | | | |
Telecanthus | | | | | | | + | | |
Epicanthus | | | | | | | | | + |
Hypertelorism | | | | | | | | | + |
Synophrys | | | + | | | | | | |
Strabismus | + | | | | | | | | |
High palate | | | + | | + | | + | | |
Trismus | | | | | + | | | | |
Smooth philtrum | | | | | + | | | | |
Protruding tongue | | | | | | | + (infancy only) | | |
Thorax/abdomen | | | | | | | | | |
Pectus excavatum | + | | + | | | | | | |
Nipples | | | | | | | | | |
Widely spaced | + | | | | | | | | |
Hypoplastic | + | | | | | | | | |
Low set | + | | | | | | | | |
Hepatomegaly | + | | | | | | | | |
Chronic diarrhoea/steatorrhoea | | | + | | | | | | |
Congenital heart disease | | | | | | | + small VSD | | |
Musculoskeletal | | | | | | | | | |
Kyphoscoliosis | | | + | | + kyphosis | | | | |
Clinodactyly V | | | +® | | + | | | | |
Camptodactyly V | | | +® | | | | | | |
Skin | | | | | | | | | |
Elbow dimples | | | | | + | | | | |
Haemangioma | | | | | | | + neck, back | | |
Other | | | | | | | | | |
Chronic serous otitis media | | | | | + | | | | |