Table 3

Linkage results from all 207 ACTANE families

Mean age at onset (y)No of familiesMax lodMap3-150NPLpMapHet lodαMapp value
⩽59 330.4917.301.600.0617.301.170.6217.300.067
60–69 71−2.8914.691.020.1510.780.590.3010.780.260
70–79 55−5.7817.300.130.44 3.830.000.001.000
⩾80 480.9510.780.310.3710.780.950.8810.780.110
Total207−9.6615.991.020.15 3.831.930.2412.080.011
  • 3-150 Map designates the genetic map distance (cM) from D1S1160 at which the maximum linkage score occurred.