Genotype and allele distributions of the BCHE WT/K polymorphism in the AD, PD, PD(B+C), and control groups
| Group | Genotypes | Alleles | |||||
|---|---|---|---|---|---|---|---|
| WW | WK | KK | W | K | |||
| AD | n=80 | 60 (0.75) | 17 (0.21) | 3 (0.04) | 137 (0.86) | 23 (0.14) | |
| PD | n=53 | 39 (0.73) | 12 (0.23) | 2 (0.04) | 90 (0.85) | 16 (0.15) | |
| PD(B+C) | n=34 | 22 (0.65) | 10 (0.29) | 2 (0.06) | 54 (0.79) | 14 (0.21) | |
| Controls | n=67 | 48 (0.72) | 18 (0.27) | 1 (0.01) | 114 (0.85) | 20 (0.15) | |
| ε4 carriers | |||||||
| AD | n=57 | 42 (0.74) | 12 (0.21) | 3 (0.05) | 96 (0.84) | 18 (0.16) | |
| PD | n=23 | 14 (0.61) | 7 (0.30) | 2 (0.09) | 35 (0.76) | 11 (0.24) | |
| PD(B+C) | n=18 | 10 (0.56) | 6 (0.33) | 2 (0.11) | 26 (0.72) | 10 (0.28) | |
| Controls | n=17 | 11 (0.65) | 5 (0.29) | 1 (0.06) | 27 (0.79) | 7 (0.21) | |
| ε4 non-carriers | |||||||
| AD | n=23 | 18 (0.78) | 5 (0.22) | 0 (0.00) | 41 (0.89) | 5 (0.11) | |
| PD | n=30 | 25 (0.83) | 5 (0.17) | 0 (0.00) | 55 (0.92) | 5 (0.08) | |
| PD(B+C) | n=16 | 12 (0.75) | 4 (0.25) | 0 (0.00) | 28 (0.88) | 4 (0.12) | |
| Controls | n=50 | 37 (0.74) | 13 (0.26) | 0 (0.00) | 87 (0.87) | 13 (0.13) | |
WW, BCHE *WT/*WT; WK,BCHE *WT/*K; KK,BCHE *K/*K; W,BCHE *WT; K, BCHE *K
n, number of subjects genotyped; frequencies shown in parentheses.