Table 2

Summary of APC mutations identified in FAP and non-FAP patients

Mutation type			FAP	Non-FAP
Base substitutions	Chain terminating mutations		35
	Amino acid changes		3	3
	Splice defects		2
Frameshifts	Insertions	1 bp	7
		2 bp	1
	Deletions	1 bp	9
		2 bp	2
		4 bp	5
		5 bp	22
		10 bp	1
PTT truncated proteins			23
Unknown			13
Total			123	3

Table summarises chain terminating mutations and amino acid changes identified in FAP and non-FAP patients; 13 patients with an unknown status are yet to be sequenced.