Chromosome abnormalities in lymphocytes of our patient; 87 metaphases were analysed
| Without Rx | After Rx1-150 (1 Gy/Go) | |
|---|---|---|
| Normal metaphases | 29 (76%) | 22(45%) |
| Abnormal metaphases | 9 (24%)1-151 | 27 (55%)1-151 |
| Rearrangement/cell | 0.34 | 1.51 |
| Rearrangement/abnormal cell | 1.44 | 2.74 |
↵1-150 Structural rearrangements (chromosome break, inversion, translocation, dicentric, triradius, unidentified marker, small acentric chromosomal fragment, ring, deletion).
Four clones showed rearrangements involving chromosome 7: t(X;7)(p11.2;q11.2), inv(7)(p22;q11.2), del(7)(p22), t(3;7)(p 13;q22).
↵1-151 For this dose in normal cells abnormal metaphases are less than 5% (only break and gap).