Table 4

Complex genetic mechanisms that have been suggested in bipolar disorder

Genetic mechanismAuthors
Locus heterogeneityHodgkinson et al 132
Allelic heterogeneitySandkuyl and Ott133
EpistasisCraddock et al 60
Dynamic mutationMcInniset al 134
ImprintingMcMahon et al 135
Mitochondrial inheritanceMcMahonet al 135
  • Genetic mechanisms causing complex patterns of inheritance and authors who have invoked the mechanisms to explain the inheritance of bipolar disorder.