Table 1

Linkage relationship between the locus for autosomal recessive RP and 14 loci from chromosome 2p11-p15 in family PMK146

Lod score (Z) at recombination fraction (θ)
0.000.010.050.100.200.300.40
D2S1352−∞−1.55−0.360.010.170.130.05
D2S1337−0.71−0.050.410.500.410.240.08
D2S3803.072.992.652.241.460.780.27
D2S4411.511.481.331.150.800.490.21
Haplotype1-150 3.383.292.942.501.650.910.33
D2S2913.022.942.632.241.480.790.25
D2S13942.562.492.201.861.190.610.18
D2S2860.471.091.391.280.840.390.09
D2S21140.571.181.481.360.890.430.11
D2S4381.841.791.621.411.000.610.27
D2S3881.921.861.651.380.870.440.13
D2S1331−0.810.070.460.440.240.080.01
D2S1258−∞−0.420.650.890.790.480.18
VSNL1−∞−4.73−2.19−1.23−0.47−0.17−0.03
  • 1-150 As no recombination was found in the region from (and including) D2S380 to D2S1394, haplotypes were constructed and used to calculate lod scores.