Distributions of chromosome 12 markers in SCA2 patients and normal controls
| Locus | Allele | npatients/N | ncontrols/N | χ2 | p |
|---|---|---|---|---|---|
| D12S84 | 3 | 1/5 | 6/120 | ||
| 7 | 2/5 | 18/120 | |||
| 8 | 1/5 | 30/120 | |||
| 10 | 1/5 | 10/120 | |||
| D12S105 | 2 | 5/5 | 61/120 | ||
| D12S1672 | 2 | 4/5 | 18/120 | 9.86 | <0.05 |
| 4 | 1/5 | 27/120 | |||
| D12S1333 | 2 | 3/4 | 8/120 | 14.71 | <0.001 |
| 7 | 1/4 | 31/120 | |||
| D12S354 | 1 | 2/5 | 43/120 | ||
| 3 | 1/5 | 17/120 | |||
| 6 | 2/5 | 39/120 | |||
| D12S79 | 5 | 3/4 | 15/120 | 7.67 | <0.05 |
| 8 | 1/4 | 4/120 |
N = number of families in which the allele segregating with the mutation could be determined or number of control chromosomes used.