Table 2

Two point lod scores at standard recombination rates and at the maximum likelihood estimate of the recombination fraction (Zmax and θmax), equal recombination rates in both sexes, for markers from chromosome 2p

MarkerLocNoHet0.000.010.050.100.200.300.40Zmaxθmax
D2S13255550.82−∞2.793.773.833.272.341.163.850.08
D2S178855.550.89−∞2.503.493.583.062.171.063.590.08
D2S2186 57 5 0.93 5.99 5.90 5.50 4.97 3.85 2.61 1.25 5.99 0.00
D2S1346 59 4 0.84 6.00 5.90 5.50 4.97 3.85 2.62 1.26 6.00 0.00
D2S1348 59 4 0.80 6.00 5.90 5.50 4.97 3.85 2.62 1.26 6.00 0.00
D2S2328 61 4 0.75 4.81 4.73 4.42 4.03 3.17 2.19 1.06 4.81 0.00
D2S1356 64 5 0.85 5.12 5.04 4.72 4.29 3.37 2.33 1.14 5.12 0.00
D2S119 65 5 0.65 5.23 5.14 4.79 4.33 3.35 2.29 1.10 5.23 0.00
D2S22986690.752.374.815.074.793.842.641.265.080.04
D2S22807050.79−∞−0.08−1.98−0.600.260.290.180.300.26
D2S135273.570.901.904.154.414.143.232.171.044.420.04
D2S273973.530.751.864.164.424.163.272.201.054.440.04
  • Genetic coordinates in cM according to the Genethon map are in the column Loc. N gives the total number of different alleles encountered in the pedigree set. Het is the estimated heterozygosity value. Bold represents statistically significant lod scores where θmax = 0.00.