Severity of skull anomalies in 16 craniosynostosis families according to the sex of the carrier of the P250R FGFR3 mutation. Only genotypically and clinically examined offspring of P250R carriers were included
| 16 families | Total offspring | P250R carriers | Group 1 | Group 2 | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Brachycephaly | Plagiocephaly | No craniosynostosis | ||||||||
| Males | 19 | 17 | 6 | 6 | 5 | |||||
| Females | 27 | 19 | 13 | 4 | 2 | |||||
| Total | 46 | 36 | 19 | 10 | 7 | |||||
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