Table 2

Age related risks to first event for all cancers and for the principal site specific cancers (colorectal, endometrium, and ovary) in 76 subjects with a nt943+3 A→T MSH2 mutation. The risk of colorectal cancer in males was significantly higher than that in females (p<0.01), but the overall risk for all cancers did not differ between the two sexes

Cancer site				Age (y)
Cancer site				30	35	40	45	50	55	60
All cancers	Male	0.12	0.26	0.47	0.61	0.69	0.84	0.84
	Female	0.02	0.10	0.23	0.43	0.59	0.70	0.82
Colorectal cancer	Male	0.08	0.22	0.37	0.50	0.59	0.77	0.77
	Female	0.00	0.05	0.11	0.24	0.28	0.34	0.43
Endometrial cancer	Female	0.00	0.03	0.05	0.29	0.38	0.45	0.51
Ovarian cancer	Female	0.02	0.07	0.13	0.19	0.19	0.19	0.19