Distribution of amino acid substitutions in Spanish MEN 2 families
| Mutation | Nucleotide change | MEN 2A (n=30) | FMTC (n=6) | Other (n=13) |
|---|---|---|---|---|
| Codon 634 | ||||
| C634Y | TGC→TAC | 22 | 0 | 2 |
| C634R | TGC→CGC | 3 | 1 | 1 |
| C634W | TGC→TGG | 3 | 2 | 1 |
| C634G | TGC→GGC | 1 | 0 | 0 |
| Codon 620 | ||||
| C620S | TGC→TCC | 1 | 0 | 0 |
| Codon 618 | ||||
| C618R | TGC→CGC | 0 | 1 | 0 |
| C618F | TGC→TTC | 0 | 0 | 2 |
| Codon 611 | ||||
| C611F | TGC→TTT | 0 | 0 | 1 |
| None | 0 | 2 | 6 | |