TY - JOUR T1 - A new strategy for mapping the human genome. JF - Journal of Medical Genetics JO - J Med Genet SP - 421 LP - 424 DO - 10.1136/jmg.23.5.421 VL - 23 IS - 5 AU - D J Shaw Y1 - 1986/10/01 UR - http://jmg.bmj.com/content/23/5/421.abstract N2 - Recent advances in agarose gel electrophoresis of large DNA fragments raise the possibility of an entirely new approach to mapping mammalian genomes. In this article is discussed the potential of this technology for tackling problems such as construction of linkage maps, identifying chromosome translocation breakpoints, and moving from linked markers to genes causing diseases such as the muscular dystrophies and Huntington's chorea. ER -