Benign familial neonatal-infantile seizures

Am J Med Genet. 1983 Dec;16(4):595-9. doi: 10.1002/ajmg.1320160417.

Abstract

We report on an autosomal dominant neonatal-infantile seizure disorder and offer criteria for establishing the diagnosis and guidelines for the evaluation and treatment of this disorder. Long-term anticonvulsant treatment usually is not required. The subsequent risk of a recurrent seizure disorder depends on whether other affected relatives developed a seizure disorder later in life. This disorder may have at least two different neonatally indistinguishable forms: one having an increased empiric risk (20%) of subsequent epilepsy, and a second which carries no increased risk. These familial neonatal-infantile seizures are termed "benign" since they are not associated with subsequent psychomotor retardation.

MeSH terms

  • Adult
  • Female
  • Genes, Dominant*
  • Humans
  • Infant, Newborn
  • Male
  • Pedigree
  • Seizures / genetics*