Using the Autism Diagnostic Interview-Revised and the Autism Diagnostic Observation Schedule-Generic for the diagnosis of autism spectrum disorders in a Greek sample with a wide range of intellectual abilities

J Autism Dev Disord. 2009 Mar;39(3):414-20. doi: 10.1007/s10803-008-0639-6. Epub 2008 Aug 28.

Abstract

We studied the interrelationship between the Autism Diagnostic Observation Schedule-Generic (ADOS-G), the Autism Diagnostic Interview-Revised (ADI-R) and DSM-IV clinical diagnosis, in a Greek sample of 77 children and adolescents, referred for the assessment of a possible pervasive developmental disorder (PDD) and presenting a wide range of cognitive abilities. The agreement of the ADOS-G and the ADI-R with the clinical diagnosis was estimated as satisfactory and moderate, respectively, while both instruments presented with excellent sensitivity for the diagnosis of autistic disorder along with satisfactory specificity. ADOS-G/ADI-R agreement was estimated as fair. Our results confirm the discriminant validity of ADI-R and ADOS-G in diagnosing pervasive developmental disorders in children and adolescents with a wide range of intellectual abilities.

Publication types

  • Validation Study

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Autistic Disorder / diagnosis*
  • Autistic Disorder / epidemiology
  • Autistic Disorder / psychology
  • Child
  • Child, Preschool
  • Cognition*
  • Diagnostic and Statistical Manual of Mental Disorders
  • Female
  • Greece
  • Humans
  • Intellectual Disability / diagnosis*
  • Intellectual Disability / epidemiology
  • Intellectual Disability / psychology
  • Intelligence*
  • Logistic Models
  • Male
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Sex Factors
  • Time Factors
  • Young Adult