The cell nucleus and aging: tantalizing clues and hopeful promises

PLoS Biol. 2005 Nov;3(11):e395. doi: 10.1371/journal.pbio.0030395. Epub 2005 Nov 15.

Abstract

Recent evidence links structural proteins in the cell nucleus with aging.

MeSH terms

  • Aging*
  • Cell Nucleus / metabolism
  • Cell Nucleus / physiology*
  • Chromosome Aberrations
  • Chromosomes
  • Facies
  • Free Radicals
  • Genome
  • Geriatrics
  • Humans
  • Lamin Type A / genetics
  • Life Expectancy
  • Models, Biological
  • Oxidative Stress
  • Progeria / genetics*
  • Progeria / pathology

Substances

  • Free Radicals
  • Lamin Type A