Cell biology: a cellular choreographer

Nature. 2004 Mar 4;428(6978):28-9. doi: 10.1038/428028a.

Abstract

Specialized cells that form barriers such as those of the intestine adopt a distinct asymmetry. One particular protein may be a prime mover in bringing about such cellular organization.

Publication types

  • News

MeSH terms

  • AMP-Activated Protein Kinases
  • Adaptor Proteins, Signal Transducing
  • Adaptor Proteins, Vesicular Transport / metabolism
  • Animals
  • Carrier Proteins*
  • Cell Polarity*
  • Epithelial Cells / cytology*
  • Epithelial Cells / metabolism*
  • Humans
  • Intestinal Mucosa / metabolism*
  • Intestines / cytology*
  • Intracellular Signaling Peptides and Proteins
  • Membrane Proteins / metabolism
  • Mice
  • Peutz-Jeghers Syndrome
  • Phosphoproteins / metabolism
  • Protein Serine-Threonine Kinases / metabolism*
  • Zonula Occludens-1 Protein

Substances

  • Adaptor Proteins, Signal Transducing
  • Adaptor Proteins, Vesicular Transport
  • Carrier Proteins
  • Intracellular Signaling Peptides and Proteins
  • Membrane Proteins
  • Phosphoproteins
  • Stk11ip protein, mouse
  • TJP1 protein, human
  • Tjp1 protein, mouse
  • Zonula Occludens-1 Protein
  • Protein Serine-Threonine Kinases
  • Stk11 protein, mouse
  • AMP-Activated Protein Kinases