The Jewish Ashkenazi founder mutations in the BRCA1/BRCA2 genes are not found at an increased frequency in Ashkenazi patients with prostate cancer

Am J Hum Genet. 1999 Sep;65(3):921-4. doi: 10.1086/302525.
No abstract available

Publication types

  • Letter

MeSH terms

  • Age Factors
  • Aged
  • Aged, 80 and over
  • BRCA2 Protein
  • Female
  • Founder Effect*
  • Genes, BRCA1 / genetics*
  • Genes, Dominant
  • Genetic Predisposition to Disease
  • Germ-Line Mutation / genetics*
  • Humans
  • Israel / epidemiology
  • Jews / genetics*
  • Male
  • Middle Aged
  • Neoplasm Proteins / genetics*
  • Prostate-Specific Antigen / analysis
  • Prostatic Neoplasms / epidemiology
  • Prostatic Neoplasms / genetics*
  • Prostatic Neoplasms / metabolism
  • Transcription Factors / genetics*

Substances

  • BRCA2 Protein
  • Neoplasm Proteins
  • Transcription Factors
  • Prostate-Specific Antigen