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The sights along route 65

Regeneration of rod visual pigments after photobleaching requires a protein called Rpe65. Several studies clarify its role in visual physiology and pathology, including a new one that shows it is required pigment regeneration in cone cells.

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References

  1. Redmond, T.M. et al. Nature Genet. 20, 344–351 (1998).

    Article  CAS  Google Scholar 

  2. Acland, G.M. et al. Nature Genet. 28, 92–95 (2001).

    CAS  PubMed  Google Scholar 

  3. Seeliger, M.W. et al. Nature Genet. 29, 70–74 (2001).

    Article  CAS  Google Scholar 

  4. Biel, M. et al. Proc. Natl Acad. Sci. USA. 96, 7553–7557 (1999).

    Article  CAS  Google Scholar 

  5. Jaissle, G.B. et al. Invest. Ophthalmol. Visual Sci. 42, 506–513 (2001)

    CAS  Google Scholar 

  6. Crouch, R.K. et al. Invest. Ophthalmol. Visual Sci. 42, S655 (2001).

    Google Scholar 

  7. Von Lintig, J. & Vogt, K. J. Biol. Chem. 275, 11915–11920 (2000).

    Article  CAS  Google Scholar 

  8. Von Lintig, J. & Wyss, A. Arch. Biochem. Biophys. 385, 47–52 (2001).

    Article  CAS  Google Scholar 

  9. Leuenberger, M.G., Engeloch-Jarret, C. & Woggon, W.D. Angew. Chem. Int. Ed. 40, 2613–2617 (2001).

    Article  Google Scholar 

  10. McBee, J.K., Palczewski, K., Baehr, W. & Pepperberg, D.R. Prog. Retina Eye Res. 20, 469–529 (2001).

    Article  CAS  Google Scholar 

  11. Saari, J.C. Invest. Ophthalmol. Visual Sci. 41, 337–348 (2000).

    CAS  Google Scholar 

  12. Saari, J.C. Handbook Exp. Pharmacol. 139, 564–588 (1999).

    Google Scholar 

  13. Van Hooser, J.P. et al. Proc Natl Acad. Sci. USA 97, 8623–8628 (2000).

    Article  CAS  Google Scholar 

Download references

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Saari, J. The sights along route 65. Nat Genet 29, 8–9 (2001). https://doi.org/10.1038/ng0901-8

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