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Reading disability in boys and girls: No evidence for a differential genetic etiology

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Abstract

In order to test the hypothesis that genetic influences are moreimportant as a cause of reading disability in girls than in boys,composite reading performance data from identical and fraternal twinpairs were analyzed using both concordance and multiple regressionmethods. The sample included 206 identical (99 male, 107 female), 159same-sex fraternal (90 male, 69 female), and 117 opposite-sex fraternaltwin pairs, in which at least one member of each pair had readingdifficulties. Although the difference between the concordance rates forreading disabilities in female identical and same-sex fraternal twinpairs was somewhat greater (65% for identical twins vs.32% for fraternal twins) than the difference in concordance ratesfor boys (68% vs. 39%), loglinear analysis of thesecategorical data revealed that the interaction between sex, zygosity,and concordance was not significant (p > 0.70). Moreover,the heritability of reading disability(h 2 g) estimated from regression analysisof the reading performance data in males was nearly identical to that infemales (h 2 g = 0.58 and 0.59,respectively; p > 0.90). Thus, results of this studyprovide little or no evidence for the hypothesis of greater geneticinfluence on reading difficulties in girls than in boys.

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Wadsworth, S.J., Knopik, V.S. & DeFries, J. Reading disability in boys and girls: No evidence for a differential genetic etiology. Reading and Writing 13, 133–145 (2000). https://doi.org/10.1023/A:1008020426672

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