Original contributionLoss of heterozygosity of chromosome 14q in low- and high-grade meningiomas
References (47)
- et al.
Chromosomal abnormalities in meningiomas
Cancer Genet Cytogenet
(1986) - et al.
Cytogenetic studies of human brain tumors and their clinical significance
Cancer Genet Cytogenet
(1987) - et al.
Chromosome abnormalities in meningeal neoplasms: Do they correlate with histology?
Cancer Genet Cytogenet
(1994) - et al.
Chromosomal involvement secondary to -22 in human meningiomas
Cancer Genet Cytogenet
(1988) - et al.
Abnormalities of chromosome 22 in human brain tumors determined by combined cytogenetic and molecular genetic approaches
Cancer Genet Cytogenet
(1993) Colour Atlas of Neuropathology
- et al.
Cranial meningiomas
- et al.
Brain tumours: The local experience 1984–1992
J HK Med Assoc
(1992) - et al.
Tumours of the central nervous system in Chinese in Hong Kong: A histological review
Aust N Z J Surg
(1988) - et al.
Evidence for the complete inactivation of the NF2 gene in the majority of sporadic meningiomas
Nature Genet
(1994)
Combined molecular genetic studies of chromosome 22q and neurofibromatosis type 2 gene in central nervous system tumors
Neurosurgery
(1995)
NF2 gene analysis distinguishes hemangiopericytoma from meningioma
Am J Pathol
(1995)
The cytogenetic and molecular genetic analysis of meningiomas
Deletion mapping of a locus on human chromosome 22 involved in the oncogenesis of meningiomas
Predominant occurrence of somatic mutations of the NF2 gene in meningiomas and schwannomas
Genes Chromosom Cancer
(1995)
Cytogenetic studies in 50 meningiomas
Cancer Genet Cytogenet
(1988)
Allelic losses on chromosomes 14, 10 and 1 in atypical and malignant meningiomas: A genetic model of meningioma progression
Cancer Res
(1995)
World Health Organization: Histological Typing of Tumours of the Central Nervous System
(1993)
Atypical and anaplastic meningiomas: Radiology, surgery, radiotherapy and outcome
Surg Neurol
(1986)
Atypical and malignant meningiomas: A clinicopathological review
Neurosurgery
(1933)
Significance of proliferating cell nuclear antigen in predicting recurrence of intracranial meningioma
J Neurosurg
(1996)
A second-generation linkage map of the human genome
Nature
(1992)
Cited by (57)
A literature review of key molecular genetic aberrations in meningiomas: A potential role in the determination of radiosurgery outcomes
2014, World NeurosurgeryCitation Excerpt :Thus, these deletions are associated with meningioma progression, rather than initiation (1). Loss of 14q is associated with grade 2 and 3 meningiomas (1, 2, 11, 12, 19). Espinosa et al. (4) used array comparative genomic hybridization (a-CGH) to evaluate 25 meningiomas for 14q abnormalities and found such changes in 10 of 25 (40%) cases.
Primary Tumors of the Nervous System
2013, Emery and Rimoin's Principles and Practice of Medical GeneticsPathology and genetics of meningiomas
2011, Seminars in Diagnostic PathologyCitation Excerpt :At the same time, more maps of these loci have generated further lists of candidate genes,40,43 the analyses of which are yet to be reported. Loss of 14q is associated with grade II and III meningiomas38,49-53 (Figure 11B). The 14q loss may also be a predictor of early recurrence in grade I meningiomas and poorer outcome in grade III meningiomas.53-55
Cytogenetic alterations in meningioma tumors and their impact on disease outcome
2007, Medicina ClinicaMolecular genetics of meningiomas
2005, Asian Journal of SurgeryAssociation of loss of 1p and alterations of chromosome 14 in meningioma progression
2004, Cancer Genetics and Cytogenetics
Copyright © 1997 Published by Elsevier Inc.