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One-carbon, carnitine, and glutathione metabolism-related biomarkers in peripartal Holstein cows are altered by prepartal body condition
2021, Journal of Dairy ScienceCitation Excerpt :At least in nonruminants, glutathione S-transferase mu 1 (GSTM1), glutathione S-transferase α 4 (GSTA4), and glutathione peroxidase 3 (GPX3) play essential roles in inactivating pro-oxidant products such as H2O2 and other ROM in various tissues (Lee et al., 2008; Curtis et al., 2010). Isoenzymes of the alpha and mu classes are predominantly expressed in the liver (Hayes et al., 1989; Board et al., 1990; Elgendy et al., 2017). The potential role of these enzymes against oxidative tissue damage in the liver of periparturient cows has not been studied.
18S rRNA gene sequencing for environmental aflatoxigenic fungi and risk of hepatic carcinoma among exposed workers
2022, Journal of Environmental Science and Health - Part A Toxic/Hazardous Substances and Environmental Engineering
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