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Catatonic schizophrenia associated with tuberous sclerosis

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Summary

A case of catatonic schizophrenia associated with tuberous sclerosis in a white male, 42 years old at the time of writing, with symptoms developing in adolescence and without a family history of tuberous sclerosis is described. This case is of interest because of the appearance of the complete triad of symptoms of tuberous sclerosis in late adolescence. A remarkable feature is also the development of a true and classical type of catatonic schizophrenia with a rapid and severe intellectual deterioration in a previously bright patient. The case presented here confirms the already accepted and recognized fact that certain kinds of cerebral pathology or dysfunction can and do produce both mental retardation and schizophrenia in the same individual.

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Read at the Downstate Interhospital Conference at the New York State Psychiatric Institute, New York, N. Y., March 17, 1964.

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Zlotlow, M., Kleiner, S. Catatonic schizophrenia associated with tuberous sclerosis. Psych Quar 39, 466–475 (1965). https://doi.org/10.1007/BF01569479

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