Summary
A deletion of the Y chromosome at the distal portion of band q11 was found in 6 men with normal male habitus but with azoospermia. Five of them were found during a survey of 1170 subfertile males while the sixth was karyotyped because of slight bone abnormalities. These findings, together with a review of the literature, suggest that on the distal portion of the nonfluorescent segment of the long arm of the Y, factors are located controlling spermatogenesis.
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Tiepolo, L., Zuffardi, O. Localization of factors controlling spermatogenesis in the nonfluorescent portion of the human y chromosome long arm. Hum. Genet. 34, 119–124 (1976). https://doi.org/10.1007/BF00278879
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DOI: https://doi.org/10.1007/BF00278879