Biochemical and Biophysical Research Communications
Volume 265, Issue 2, 19 November 1999, Pages 335-338
Regular ArticleAssociation of the Estrogen Receptor α Gene Polymorphisms with Sporadic Alzheimer's Disease
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2019, Alzheimer's and DementiaCitation Excerpt :Two further SNPs (COMT rs4680 G/G; ppxx genotype of ESR1) were studied in small numbers of APOE ε4/ε4 cases and controls. As a result, despite a positive RF being calculated, these studies had weak evidence with nonsignificant P values and wide confidence intervals for the ORs and hence categorized as inconclusive [9,10]. The RF for ALDH2 A-/A- (rs1229984) was close to 1 and hence was categorized as having neutral effect [11].
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- 1
To whom correspondence should be addressed at Department of Clinical Physiopathology, University of Florence, Viale Pieraccini 6, 50139 Florence, Italy. Fax: 0039-55-2337867. E-mail: [email protected].
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