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Original Article
Contribution of de novo and mosaic TP53 mutations to Li-Fraumeni syndrome

Authors

  • Mariette Renaux-Petel Department of Genetics, Normandy Centre for Genomic and Personalized Medicine, Normandie University, UNIROUEN, Inserm U1245 and Rouen University Hospital, Rouen, FranceDepartment of Paediatric Surgery, Rouen University Hospital, Rouen, France PubMed articlesGoogle scholar articles
  • Françoise Charbonnier Department of Genetics, Normandy Centre for Genomic and Personalized Medicine, Normandie University, UNIROUEN, Inserm U1245 and Rouen University Hospital, Rouen, France PubMed articlesGoogle scholar articles
  • Jean-Christophe Théry Department of Genetics, Normandy Centre for Genomic and Personalized Medicine, Normandie University, UNIROUEN, Inserm U1245 and Rouen University Hospital, Rouen, FranceDepartment of Medical Oncology, Henri Becquerel Centre, Rouen, France PubMed articlesGoogle scholar articles
  • Pierre Fermey Department of Genetics, Normandy Centre for Genomic and Personalized Medicine, Normandie University, UNIROUEN, Inserm U1245 and Rouen University Hospital, Rouen, France PubMed articlesGoogle scholar articles
  • Gwendoline Lienard Department of Genetics, Normandy Centre for Genomic and Personalized Medicine, Normandie University, UNIROUEN, Inserm U1245 and Rouen University Hospital, Rouen, France PubMed articlesGoogle scholar articles
  • Jacqueline Bou Department of Genetics, Normandy Centre for Genomic and Personalized Medicine, Normandie University, UNIROUEN, Inserm U1245 and Rouen University Hospital, Rouen, France PubMed articlesGoogle scholar articles
  • Sophie Coutant Department of Genetics, Normandy Centre for Genomic and Personalized Medicine, Normandie University, UNIROUEN, Inserm U1245 and Rouen University Hospital, Rouen, France PubMed articlesGoogle scholar articles
  • Myriam Vezain Department of Genetics, Normandy Centre for Genomic and Personalized Medicine, Normandie University, UNIROUEN, Inserm U1245 and Rouen University Hospital, Rouen, France PubMed articlesGoogle scholar articles
  • Edwige Kasper Department of Genetics, Normandy Centre for Genomic and Personalized Medicine, Normandie University, UNIROUEN, Inserm U1245 and Rouen University Hospital, Rouen, France PubMed articlesGoogle scholar articles
  • Steeve Fourneaux Department of Genetics, Normandy Centre for Genomic and Personalized Medicine, Normandie University, UNIROUEN, Inserm U1245 and Rouen University Hospital, Rouen, France PubMed articlesGoogle scholar articles
  • Sandrine Manase Department of Genetics, Normandy Centre for Genomic and Personalized Medicine, Normandie University, UNIROUEN, Inserm U1245 and Rouen University Hospital, Rouen, France PubMed articlesGoogle scholar articles
  • Maud Blanluet Department of Genetics, Normandy Centre for Genomic and Personalized Medicine, Normandie University, UNIROUEN, Inserm U1245 and Rouen University Hospital, Rouen, France PubMed articlesGoogle scholar articles
  • Bruno Leheup Department of Clinical Genetics, Nancy University Hospital, Nancy, France PubMed articlesGoogle scholar articles
  • Ludovic Mansuy Department of Paediatric Oncology, Nancy University Hospital, Nancy, France PubMed articlesGoogle scholar articles
  • Jacqueline Champigneulle Department of Pathology, Nancy University Hospital, Nancy, France PubMed articlesGoogle scholar articles
  • Céline Chappé Department of Paediatric Oncology, Rennes University Hospital, Rennes, France PubMed articlesGoogle scholar articles
  • Michel Longy Department of Molecular Genetics, Bergonié Institute, Bordeaux, France PubMed articlesGoogle scholar articles
  • Nicolas Sévenet Department of Molecular Genetics, Bergonié Institute, Bordeaux, France PubMed articlesGoogle scholar articles
  • Brigitte Bressac-de Paillerets Department of Medical Biology and Pathology, and Inserm U1186, Gustave Roussy, University of Paris-Saclay, Villejuif, France PubMed articlesGoogle scholar articles
  • Léa Guerrini-Rousseau Child and Adolescent Cancer Department, Gustave Roussy Cancer Campus, Villejuif, France PubMed articlesGoogle scholar articles
  • Laurence Brugières Child and Adolescent Cancer Department, Gustave Roussy Cancer Campus, Villejuif, France PubMed articlesGoogle scholar articles
  • Olivier Caron Department of Oncology, Gustave Roussy Cancer Campus, Villejuif, France PubMed articlesGoogle scholar articles
  • Jean-Christophe Sabourin Department of Genetics, Normandy Centre for Genomic and Personalized Medicine, Normandie University, UNIROUEN, Inserm U1245 and Rouen University Hospital, Rouen, FranceDepartment of Pathology, Rouen University Hospital, Rouen, France PubMed articlesGoogle scholar articles
  • Isabelle Tournier Department of Genetics, Normandy Centre for Genomic and Personalized Medicine, Normandie University, UNIROUEN, Inserm U1245 and Rouen University Hospital, Rouen, France PubMed articlesGoogle scholar articles
  • Stéphanie Baert-Desurmont Department of Genetics, Normandy Centre for Genomic and Personalized Medicine, Normandie University, UNIROUEN, Inserm U1245 and Rouen University Hospital, Rouen, France PubMed articlesGoogle scholar articles
  • Thierry Frébourg Department of Genetics, Normandy Centre for Genomic and Personalized Medicine, Normandie University, UNIROUEN, Inserm U1245 and Rouen University Hospital, Rouen, France PubMed articlesGoogle scholar articles
  • Gaëlle Bougeard Department of Genetics, Normandy Centre for Genomic and Personalized Medicine, Normandie University, UNIROUEN, Inserm U1245 and Rouen University Hospital, Rouen, France PubMed articlesGoogle scholar articles
  1. Correspondence to Professor Thierry Frébourg, Department of Genetics, Rouen University Hospital, Inserm U1245, IRIB, Normandy Centre for Genomic and Personalized Medicine, Faculty of Medicine, 22 boulevard Gambetta, 76183 Rouen CEDEX 1, France; thierry.frebourg{at}chu-rouen.fr
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Citation

Renaux-Petel M, Charbonnier F, Théry J, et al
Contribution of de novo and mosaic TP53 mutations to Li-Fraumeni syndrome

Publication history

  • Received 11 August 2017
  • Revised 28 September 2017
  • Accepted 9 October 2017
  • Published in print 23 October 2017.
  • Published online 25 October 2017.

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