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Original Article
Genetic landscape of interactive effects of HLA-DRB1 alleles on susceptibility to ACPA(+) rheumatoid arthritis and ACPA levels in Japanese population

Authors

  • Chikashi Terao Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, JapanCenter for the Promotion of Interdisciplinary Education and Research, Kyoto University, Kyoto, JapanDivision of Rheumatology, Immunology, and Allergy, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USADivision of Genetics, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USAProgram in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Yukinori Okada Department of Statistical Genetics, Osaka University Graduate School of Medicine, Osaka, JapanLaboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, JapanLaboratory of Statistical Immunology, Immunology, Frontier Research Center (WPI-IFReC), Osaka University, Suita, Japan PubMed articlesGoogle scholar articles
  • Katsunori Ikari Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, JapanCore Research for Evolutional Science and Technology, Japan Science and Technology Agency, Kyoto, Japan PubMed articlesGoogle scholar articles
  • Yuta Kochi Laboratory for Autoimmune Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan PubMed articlesGoogle scholar articles
  • Akari Suzuki Laboratory for Autoimmune Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan PubMed articlesGoogle scholar articles
  • Koichiro Ohmura Department of Rheumatology and Clinical Immunology, Kyoto University Graduate School of Medicine, Kyoto, Japan PubMed articlesGoogle scholar articles
  • Keitaro Matsuo Division of Molecular and Clinical Epidemiology, Aichi Cancer Center Research Institute, Nagoya, Japan PubMed articlesGoogle scholar articles
  • Atsuo Taniguchi Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan PubMed articlesGoogle scholar articles
  • Michiaki Kubo Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan PubMed articlesGoogle scholar articles
  • Soumya Raychaudhuri Division of Rheumatology, Immunology, and Allergy, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USADivision of Genetics, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, USAProgram in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USAArthritis Research UK Epidemiology Unit, Musculoskeletal Research Group, University of Manchester, Manchester Academic Health Sciences Centre, Manchester, UK PubMed articlesGoogle scholar articles
  • Kazuhiko Yamamoto Laboratory for Autoimmune Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan PubMed articlesGoogle scholar articles
  • Hisashi Yamanaka Institute of Rheumatology, Tokyo Women’s Medical University, Tokyo, Japan PubMed articlesGoogle scholar articles
  • Yoichiro Kamatani Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan PubMed articlesGoogle scholar articles
  • Tsuneyo Mimori Department of Rheumatology and Clinical Immunology, Kyoto University Graduate School of Medicine, Kyoto, Japan PubMed articlesGoogle scholar articles
  • Fumihiko Matsuda Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Chikashi Terao, Division of Rheumatology, Immunology, and Allergy, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA; a0001101{at}kuhp.kyoto-u.ac.jp
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Citation

Terao C, Okada Y, Ikari K, et al
Genetic landscape of interactive effects of HLA-DRB1 alleles on susceptibility to ACPA(+) rheumatoid arthritis and ACPA levels in Japanese population

Publication history

  • Received 4 May 2017
  • Revised 28 August 2017
  • Accepted 18 September 2017
  • Published online 12 October 2017.

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