Cochrane1 proposed that, because resources are always limited, they should be used to provide equitably those forms of health care which have been shown in properly designed evaluations to be effective. Consistently with this suggestion, Antoniou and colleagues2 examined the performance of several algorithms for predicting the BRCA1 and BRCA2 mutation status of women attending UK cancer family clinics over the last decade or so. They concluded, not unreasonably, that the widespread use of these models would "improve equity of access and the cost-effectiveness of genetic testing". However they did not describe policy changes which would achieve these gains.
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