Termination of damaged protein repair defines the occurrence of symptoms in carriers of the m.3243A&gt;G tRNALeu mutation

R G E van Eijsden; L M T Eijssen; P J Lindsey; C M M van den Burg; L E A de Wit; M E Rubio-Gozalbo; C E M de Die; T Ayoubi; W Sluiter; I F M de Coo; H J M Smeets

doi:10.1136/jmg.2008.057497

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Termination of damaged protein repair defines the occurrence of symptoms in carriers of the m.3243A>G tRNA^Leu mutation

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	Abstract	Full	Pdf
May 2008	49	0	45
Jun 2008	15	0	25
Jul 2008	10	0	22
Aug 2008	101	26	40
Sep 2008	81	19	17
Oct 2008	39	7	8
Nov 2008	47	29	5
Dec 2008	24	9	4
Jan 2009	34	7	6
Feb 2009	15	17	13
Mar 2009	80	5	9
Apr 2009	17	8	8
May 2009	19	1	2
Jun 2009	17	5	10
Jul 2009	22	3	3
Aug 2009	18	7	3
Sep 2009	27	6	4
Oct 2009	19	2	0
Nov 2009	19	4	4
Dec 2009	108	6	3
Jan 2010	45	1	3
Feb 2010	49	1	1
Mar 2010	34	3	1
Apr 2010	47	6	1
May 2010	114	2	1
Jun 2010	60	3	5
Jul 2010	104	8	9
Aug 2010	66	4	9
Sep 2010	88	8	3
Oct 2010	40	10	4
Nov 2010	30	8	4
Dec 2010	16	5	3
Jan 2011	18	7	5
Feb 2011	19	10	2
Mar 2011	18	5	13
Apr 2011	17	1	6
May 2011	12	5	13
Jun 2011	14	6	5
Jul 2011	30	2	2
Aug 2011	31	3	6
Sep 2011	10	6	5
Oct 2011	22	4	1
Nov 2011	37	2	2
Dec 2011	21	2	2
Jan 2012	45	2	2
Feb 2012	16	4	3
Mar 2012	29	2	2
Apr 2012	25	2	0
May 2012	23	2	1
Jun 2012	13	1	1
Jul 2012	22	6	2
Aug 2012	31	5	2
Sep 2012	24	2	2
Oct 2012	26	0	0
Nov 2012	21	3	2
Dec 2012	33	1	1
Jan 2013	40	0	0
Feb 2013	19	2	2
Mar 2013	40	1	1
Apr 2013	34	0	1
May 2013	23	1	3
Jun 2013	11	5	3
Jul 2013	5	0	1
Aug 2013	11	0	0
Sep 2013	10	0	0
Oct 2013	13	0	0
Nov 2013	21	0	0
Dec 2013	13	0	0
Jan 2014	12	0	0
Feb 2014	14	0	0
Mar 2014	15	1	1
Apr 2014	20	0	0
May 2014	23	3	2
Jun 2014	14	1	2
Jul 2014	19	0	1
Aug 2014	19	1	2
Sep 2014	12	1	0
Oct 2014	10	2	0
Nov 2014	11	0	1
Dec 2014	14	7	2
Jan 2015	9	1	0
Feb 2015	5	0	1
Mar 2015	14	1	1
Apr 2015	6	0	0
May 2015	7	0	2
Jun 2015	18	0	1
Jul 2015	7	1	2
Aug 2015	8	0	0
Sep 2015	27	0	0
Oct 2015	8	0	0
Nov 2015	10	1	0
Dec 2015	19	1	1
Jan 2016	19	1	0
Feb 2016	14	0	1
Mar 2016	9	1	2
Apr 2016	9	0	0
May 2016	9	0	1
Jun 2016	12	0	0
Jul 2016	10	1	1
Aug 2016	7	0	1
Sep 2016	21	1	2
Oct 2016	10	0	0
Nov 2016	19	0	0
Dec 2016	15	0	0
Jan 2017	16	0	0
Feb 2017	4	1	0
Mar 2017	23	6	4
Apr 2017	9	2	1
May 2017	11	0	0
Jun 2017	15	1	0
Jul 2017	14	0	0
Aug 2017	28	1	0
Sep 2017	28	0	0
Oct 2017	36	0	0
Nov 2017	35	0	0
Dec 2017	22	0	0
Jan 2018	38	1	1
Feb 2018	21	1	0
Mar 2018	20	0	0
Apr 2018	32	0	0
May 2018	16	1	2
Jun 2018	22	0	0
Jul 2018	20	1	0
Aug 2018	48	0	0
Sep 2018	30	0	1
Oct 2018	25	1	0
Nov 2018	46	1	1
Dec 2018	33	0	0
Jan 2019	32	0	0
Feb 2019	18	1	0
Mar 2019	13	0	0
Apr 2019	31	0	0
May 2019	27	0	2
Jun 2019	4	2	0
Jul 2019	13	1	0
Aug 2019	9	1	1
Sep 2019	14	0	0
Oct 2019	40	0	0
Nov 2019	6	0	0
Dec 2019	20	0	0
Jan 2020	63	0	0
Feb 2020	44	0	0
Mar 2020	18	1	1
Apr 2020	11	0	3
May 2020	29	2	1
Jun 2020	29	0	0
Jul 2020	18	0	0
Aug 2020	8	0	0
Sep 2020	34	3	2
Oct 2020	22	2	1
Nov 2020	47	0	0
Dec 2020	21	1	0
Jan 2021	32	0	0
Feb 2021	24	1	0
Mar 2021	46	2	2
Apr 2021	30	4	1
May 2021	9	2	0
Jul 2021	1	1	0
Aug 2021	1	0	0
Oct 2021	38	2	2
Nov 2021	26	2	0
Dec 2021	26	0	2
Jan 2022	17	1	0
Feb 2022	68	0	0
Mar 2022	36	2	2
Apr 2022	20	0	2
May 2022	65	1	0
Jun 2022	51	1	0
Jul 2022	35	2	0
Aug 2022	57	4	0
Sep 2022	41	1	0
Oct 2022	53	1	3
Nov 2022	30	0	0
Dec 2022	10	0	0
Jan 2023	18	0	0
Feb 2023	50	0	0
Mar 2023	4	0	0
Apr 2023	17	1	1
May 2023	15	1	0
Jun 2023	9	0	0
Jul 2023	10	0	0
Aug 2023	11	0	0
Sep 2023	8	4	1
Oct 2023	10	0	0
Nov 2023	32	0	0
Dec 2023	25	1	2
Jan 2024	27	0	0
Feb 2024	14	0	0
Mar 2024	13	0	0
Total	4868	402	432

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