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Genome-wide studies
Original article
Meta-analysis of genome-wide association studies of HDL cholesterol response to statins

Authors

  • Iris Postmus Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands PubMed articlesGoogle scholar articles
  • Helen R Warren Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK Barts NIHR Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, EC1M 6BQ, UK PubMed articlesGoogle scholar articles
  • Stella Trompet Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands PubMed articlesGoogle scholar articles
  • Benoit J Arsenault Montreal Heart Institute, Université de Montréal, Montreal, Canada PubMed articlesGoogle scholar articles
  • Christy L Avery Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina, USA PubMed articlesGoogle scholar articles
  • Joshua C Bis Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA PubMed articlesGoogle scholar articles
  • Daniel I Chasman Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Catherine E de Keyser Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands PubMed articlesGoogle scholar articles
  • Harshal A Deshmukh Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK PubMed articlesGoogle scholar articles
  • Daniel S Evans California Pacific Medical Center Research Institute, San Francisco, California, USA PubMed articlesGoogle scholar articles
  • QiPing Feng Department of Clinical Pharmacology, Vanderbilt University, Nashville, Tennessee, USA PubMed articlesGoogle scholar articles
  • Xiaohui Li Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute and Departments of Pediatrics and Medicine at Harbor-UCLA Medical Center, Torrance, California, USA PubMed articlesGoogle scholar articles
  • Roelof A J Smit Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands PubMed articlesGoogle scholar articles
  • Albert V Smith Icelandic Heart Association, Kopavogur, Iceland Department of Medicine, University of Iceland, Reykjavik, Iceland PubMed articlesGoogle scholar articles
  • Fangui Sun Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Kent D Taylor Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute and Departments of Pediatrics and Medicine at Harbor-UCLA Medical Center, Torrance, California, USA PubMed articlesGoogle scholar articles
  • Alice M Arnold Department of Biostatistics, University of Washington, Seattle, Washington, USA PubMed articlesGoogle scholar articles
  • Michael R Barnes Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK Barts NIHR Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, EC1M 6BQ, UK PubMed articlesGoogle scholar articles
  • Bryan J Barratt Personalised Healthcare and Biomarkers AstraZeneca Research and Development, Alderley Park, UK PubMed articlesGoogle scholar articles
  • John Betteridge University College London Hospital, London, UK PubMed articlesGoogle scholar articles
  • S Matthijs Boekholdt Department of Cardiology, Academic Medical Center, Amsterdam, North Holland, Netherlands PubMed articlesGoogle scholar articles
  • Eric Boerwinkle Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, Texas, USA PubMed articlesGoogle scholar articles
  • Brendan M Buckley Department of Pharmacology and Therapeutics, University College Cork, Western Road, Cork, Ireland PubMed articlesGoogle scholar articles
  • Y-D Ida Chen Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute and Departments of Pediatrics and Medicine at Harbor-UCLA Medical Center, Torrance, California, USA PubMed articlesGoogle scholar articles
  • Anton J M de Craen Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands PubMed articlesGoogle scholar articles
  • Steven R Cummings California Pacific Medical Center Research Institute, San Francisco, California, USA PubMed articlesGoogle scholar articles
  • Joshua C Denny Department of Biomedical Informatics, Vanderbilt University, Nashville, Tennessee, USA Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA PubMed articlesGoogle scholar articles
  • Marie Pierre Dubé Montreal Heart Institute, Université de Montréal, Montreal, Canada PubMed articlesGoogle scholar articles
  • Paul N Durrington Cardiovascular Research Group, School of Biosciences, University of Manchester, Manchester, UK PubMed articlesGoogle scholar articles
  • Gudny Eiriksdottir Icelandic Heart Association, Kopavogur, Iceland PubMed articlesGoogle scholar articles
  • Ian Ford Robertson Center for Biostatistics, University of Glasgow, Glasgow, UK PubMed articlesGoogle scholar articles
  • Xiuqing Guo Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute and Departments of Pediatrics and Medicine at Harbor-UCLA Medical Center, Torrance, California, USA PubMed articlesGoogle scholar articles
  • Tamara B Harris Laboratory of Epidemiology, Demography, Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA PubMed articlesGoogle scholar articles
  • Susan R Heckbert Department of Epidemiology, University of Washington, Seattle, Washington, USA Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA Group Health Research Institute, Group Health Cooperative, Seattle, Washington, USA PubMed articlesGoogle scholar articles
  • Albert Hofman Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands The Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands PubMed articlesGoogle scholar articles
  • G Kees Hovingh Department of Vascular Medicine, Academic Medical Center, Amsterdam, North Holland, Netherlands PubMed articlesGoogle scholar articles
  • John J P Kastelein Department of Vascular Medicine, Academic Medical Center, Amsterdam, North Holland, Netherlands PubMed articlesGoogle scholar articles
  • Leonore J Launer Laboratory of Epidemiology, Demography, Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA PubMed articlesGoogle scholar articles
  • Ching-Ti Liu Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Yongmei Liu Department of Epidemiology and Prevention, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA PubMed articlesGoogle scholar articles
  • Thomas Lumley Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA Department of Statistic, University of Auckland, Auckland, New Zealand PubMed articlesGoogle scholar articles
  • Paul M McKeigue Centre for Population Health Sciences, University of Edinburgh, Edinburgh, UK PubMed articlesGoogle scholar articles
  • Patricia B Munroe Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK Barts NIHR Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, EC1M 6BQ, UK PubMed articlesGoogle scholar articles
  • Andrew Neil Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK PubMed articlesGoogle scholar articles
  • Deborah A Nickerson Department of Genome Sciences, University of Washington, Seattle, Washington, USA PubMed articlesGoogle scholar articles
  • Fredrik Nyberg Medical Evidence and Observational Research, AstraZeneca Gothenburg, Mölndal, Sweden Unit of Occupational and Environmental Medicine, University of Gothenburg, Gothenburg, Sweden PubMed articlesGoogle scholar articles
  • Eoin O'Brien The Conway Institute, University College Dublin, Dublin 4, Ireland PubMed articlesGoogle scholar articles
  • Christopher J O'Donnell Framingham Heart Study, National Heart, Lung, and Blood Institute, Framingham, Massachusetts, USA Cardiology Division, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA NHLBI Division of Intramural Research, Bethesda, Maryland, USA PubMed articlesGoogle scholar articles
  • Wendy Post Department of Cardiology, Johns Hopkins University, Baltimore, Maryland, USA PubMed articlesGoogle scholar articles
  • Neil Poulter International Centre for Circulatory Health, Imperial College London, London, UK PubMed articlesGoogle scholar articles
  • Ramachandran S Vasan Section of Preventive Medicine and Epidemiology, Department of Medicine, Boston University School of Medicine, and the Framingham Heart Study, Framingham, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Kenneth Rice Department of Biostatistics, University of Washington, Seattle, Washington, USA PubMed articlesGoogle scholar articles
  • Stephen S Rich Center for Public Health Genomics, University of Virginia, Charlottesville, Virginia, USA PubMed articlesGoogle scholar articles
  • Fernando Rivadeneira Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands PubMed articlesGoogle scholar articles
  • Naveed Sattar Institute of Cardiovascular and Medical Science, University of Glasgow, Glasgow, Scotland PubMed articlesGoogle scholar articles
  • Peter Sever International Centre for Circulatory Health, Imperial College London, London, UK PubMed articlesGoogle scholar articles
  • Sue Shaw-Hawkins Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK Barts NIHR Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, EC1M 6BQ, UK PubMed articlesGoogle scholar articles
  • Denis C Shields The Conway Institute, University College Dublin, Dublin 4, Ireland School of Medicine and Medical Sciences, University College Dublin, Dublin, Ireland PubMed articlesGoogle scholar articles
  • P Eline Slagboom Department of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands PubMed articlesGoogle scholar articles
  • Nicholas L Smith Department of Epidemiology, University of Washington, Seattle, Washington, USA Group Health Research Institute, Group Health Cooperative, Seattle, Washington, USA Department of Veterans Affairs Office of Research and Development, Seattle Epidemiologic Research and Information Center, Seattle, Washington, USA PubMed articlesGoogle scholar articles
  • Joshua D Smith Department of Genome Sciences, University of Washington, Seattle, Washington, USA PubMed articlesGoogle scholar articles
  • Nona Sotoodehnia Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA Division of Cardiology, Harborview Medical Center, University of Washington, Seattle, Washington, USA PubMed articlesGoogle scholar articles
  • Alice Stanton Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland Beaumont Hospital, Dublin, Ireland PubMed articlesGoogle scholar articles
  • David J Stott Faculty of Medicine, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK PubMed articlesGoogle scholar articles
  • Bruno H Stricker Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands Inspectorate of Health Care, the Hague, the Netherlands PubMed articlesGoogle scholar articles
  • Til Stürmer Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina, USA PubMed articlesGoogle scholar articles
  • André G Uitterlinden Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands The Netherlands Consortium for Healthy Ageing, Leiden, The Netherlands Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands PubMed articlesGoogle scholar articles
  • Wei-Qi Wei Department of Biomedical Informatics, Vanderbilt University, Nashville, Tennessee, USA PubMed articlesGoogle scholar articles
  • Rudi G J Westendorp Department of Public Health, Center for Healthy Ageing, University of Copenhagen, Copenhagen, Denmark PubMed articlesGoogle scholar articles
  • Eric A Whitsel Department of Epidemiology, University of North Carolina, Chapel Hill, North Carolina, USA Department of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA PubMed articlesGoogle scholar articles
  • Kerri L Wiggins Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA PubMed articlesGoogle scholar articles
  • Russell A Wilke Department of Internal Medicine, Sanford Healthcare, Sioux Falls, South Dakota, USA Department of Medicine, University of South Dakota, Sioux Falls, South Dakota, USA PubMed articlesGoogle scholar articles
  • Christie M Ballantyne Department of Medicine, Baylor College of Medicine, Houston, Texas, USA PubMed articlesGoogle scholar articles
  • Helen M Colhoun Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK Department of Public Health, University of Dundee, Dundee, UK PubMed articlesGoogle scholar articles
  • L Adrienne Cupples Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA Framingham Heart Study, National Heart, Lung, and Blood Institute, Framingham, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Oscar H Franco Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands PubMed articlesGoogle scholar articles
  • Vilmundur Gudnason Icelandic Heart Association, Kopavogur, Iceland Department of Medicine, University of Iceland, Reykjavik, Iceland PubMed articlesGoogle scholar articles
  • Graham Hitman Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK PubMed articlesGoogle scholar articles
  • Colin N A Palmer Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, UK PubMed articlesGoogle scholar articles
  • Bruce M Psaty Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA Department of Epidemiology, University of Washington, Seattle, Washington, USA Group Health Research Institute, Group Health Cooperative, Seattle, Washington, USA Department of Health Services, University of Washington, Seattle, Washington, USA PubMed articlesGoogle scholar articles
  • Paul M Ridker Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Jeanette M Stafford Department of Biostatistical Sciences, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA PubMed articlesGoogle scholar articles
  • Charles M Stein Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA Department of Pharmacology, Vanderbilt University, Nashville, Tennessee, USA PubMed articlesGoogle scholar articles
  • Jean-Claude Tardif Montreal Heart Institute, Université de Montréal, Montreal, Canada PubMed articlesGoogle scholar articles
  • Mark J Caulfield Department of Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK Barts NIHR Cardiovascular Biomedical Research Unit, Queen Mary University of London, London, EC1M 6BQ, UK PubMed articlesGoogle scholar articles
  • J Wouter Jukema Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands Durrer Center for Cardiogenetic Research, Amsterdam, The Netherlands Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands PubMed articlesGoogle scholar articles
  • Jerome I Rotter Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute and Departments of Pediatrics and Medicine at Harbor-UCLA Medical Center, Torrance, California, USA PubMed articlesGoogle scholar articles
  • Ronald M Krauss Department of Atherosclerosis Research, Children's Hospital Oakland Research Institute, Oakland, California, USA PubMed articlesGoogle scholar articles
  1. Correspondence to Ronald M Krauss, Children's Hospital Oakland Research Institute, 5700 Martin Luther King Jr. Way, Oakland, CA 94609, USA; rkrauss{at}chori.org
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Citation

Postmus I, Warren HR, Trompet S, et al
Meta-analysis of genome-wide association studies of HDL cholesterol response to statins
Journal of Medical Genetics 2016;53:835-845.

Publication history

  • Received April 18, 2016
  • Revised July 3, 2016
  • Accepted July 26, 2016
  • First published September 1, 2016.
Online issue publication 
November 23, 2016

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