Ten-year outcome of enzyme replacement therapy with agalsidase beta in patients with Fabry disease

Dominique P Germain; Joel Charrow; Robert J Desnick; Nathalie Guffon; Judy Kempf; Robin H Lachmann; Roberta Lemay; Gabor E Linthorst; Seymour Packman; C Ronald Scott; Stephen Waldek; David G Warnock; Neal J Weinreb; William R Wilcox

doi:10.1136/jmedgenet-2014-102797

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Therapeutics

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Ten-year outcome of enzyme replacement therapy with agalsidase beta in patients with Fabry disease

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Mar 2015	228	256	179
Apr 2015	519	502	334
May 2015	405	219	181
Jun 2015	156	106	98
Jul 2015	139	107	89
Aug 2015	87	119	74
Sep 2015	127	108	46
Oct 2015	41	67	36
Nov 2015	75	89	69
Dec 2015	75	69	45
Jan 2016	81	91	56
Feb 2016	66	87	46
Mar 2016	35	81	53
Apr 2016	29	63	47
May 2016	34	60	48
Jun 2016	41	93	56
Jul 2016	47	46	33
Aug 2016	43	70	43
Sep 2016	55	65	25
Oct 2016	56	94	44
Nov 2016	54	89	30
Dec 2016	30	52	18
Jan 2017	51	63	40
Feb 2017	15	51	34
Mar 2017	18	71	41
Apr 2017	14	114	47
May 2017	15	101	40
Jun 2017	33	89	33
Jul 2017	79	71	21
Aug 2017	94	76	31
Sep 2017	135	107	37
Oct 2017	109	86	43
Nov 2017	214	168	43
Dec 2017	196	179	21
Jan 2018	235	201	35
Feb 2018	187	152	42
Mar 2018	308	266	38
Apr 2018	199	149	31
May 2018	175	157	47
Jun 2018	118	98	31
Jul 2018	139	107	38
Aug 2018	153	127	42
Sep 2018	177	153	48
Oct 2018	203	165	51
Nov 2018	215	189	35
Dec 2018	190	177	24
Jan 2019	186	160	33
Feb 2019	162	139	37
Mar 2019	116	99	41
Apr 2019	122	90	44
May 2019	109	97	40
Jun 2019	108	84	41
Jul 2019	124	108	45
Aug 2019	126	104	44
Sep 2019	122	102	35
Oct 2019	163	110	50
Nov 2019	97	84	30
Dec 2019	94	76	22
Jan 2020	167	134	56
Feb 2020	126	105	40
Mar 2020	122	109	41
Apr 2020	99	83	38
May 2020	101	89	34
Jun 2020	104	67	36
Jul 2020	97	77	80
Aug 2020	96	73	44
Sep 2020	152	136	55
Oct 2020	113	81	49
Nov 2020	113	82	54
Dec 2020	91	77	50
Jan 2021	92	77	41
Feb 2021	149	120	47
Mar 2021	131	111	61
Apr 2021	155	126	51
May 2021	151	131	46
Jun 2021	83	81	48
Jul 2021	166	166	60
Aug 2021	142	142	40
Sep 2021	251	251	63
Oct 2021	208	202	66
Nov 2021	179	157	59
Dec 2021	176	172	34
Jan 2022	199	176	55
Feb 2022	207	201	78
Mar 2022	225	220	33
Apr 2022	215	205	49
May 2022	229	206	48
Jun 2022	259	253	70
Jul 2022	184	165	55
Aug 2022	201	179	47
Sep 2022	303	282	50
Oct 2022	279	255	60
Nov 2022	320	286	74
Dec 2022	242	224	105
Jan 2023	231	224	52
Feb 2023	259	227	45
Mar 2023	275	231	67
Apr 2023	241	211	46
May 2023	256	253	51
Jun 2023	310	288	42
Jul 2023	241	234	34
Aug 2023	205	198	33
Sep 2023	219	201	36
Oct 2023	282	258	38
Nov 2023	325	318	50
Dec 2023	377	366	33
Jan 2024	173	170	126
Feb 2024	178	173	42
Mar 2024	207	201	184
Total	17130	15957	5801

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